New drug targets Hard-to-Treat cancers with PIK3CA mutation

NCT ID NCT07383506

First seen Feb 03, 2026 · Last updated May 13, 2026 · Updated 12 times

Summary

This early-phase study tests an experimental drug called CGT6297 in 90 adults whose advanced solid tumors (including certain breast and endometrial cancers) have a specific genetic change called PIK3CA. The main goals are to check the drug's safety and find the best dose, while also seeing if it can shrink tumors. Participants must have a PIK3CA mutation and have tried other treatments first.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NEXT Austin

    Austin, Texas, 78758, United States

  • NEXT Virginia

    Fairfax, Virginia, 22031, United States

Conditions

Explore the condition pages connected to this study.