New drug targets Hard-to-Treat cancers with PIK3CA mutation

NCT ID NCT07383506

First seen Feb 03, 2026 · Last updated Jun 16, 2026 · Updated 18 times

Summary

This early-phase study tests an experimental drug called CGT6297 in about 90 adults whose advanced solid tumors (including certain breast and endometrial cancers) have a specific genetic change called PIK3CA. The main goals are to find a safe dose and see if the drug can shrink or control the tumors. Participants will receive the drug and be closely monitored for side effects and tumor response.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NEXT Austin

    RECRUITING

    Austin, Texas, 78758, United States

  • NEXT Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

Conditions

Explore the condition pages connected to this study.