Can CF drugs tame diabetes in cystic fibrosis?

NCT ID NCT07102043

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether CFTR modulators (ETI) help control blood sugar in people with cystic fibrosis-related diabetes (CFRD). Researchers will compare 30 adults with CFRD who take ETI to those who cannot take it. The goal is to see if the drug improves how the body handles sugar after meals.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CFTR modulator (elexacaftor/tezacaftor/ivacaftor, ETI)

What this could lead to

If successful, this could clarify whether CFTR modulators improve blood sugar regulation in cystic fibrosis-related diabetes, pointing toward better management strategies.

What could go wrong

This is a small observational study (30 people) measuring metabolic markers, not clinical outcomes. It may not prove direct benefit or apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis-related diabetes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 352294, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••