Could a single CF gene copy change your infection risk?
NCT ID NCT05474430
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is recruiting 160 people — half who carry one copy of the cystic fibrosis (CF) gene and half who do not — to see if carriers have different risks for respiratory infections. Researchers will collect nasal cells and blood samples to measure how well the cells move chloride and bicarbonate, how acidic the airway surface is, and how thick mucus is. The goal is to understand whether carrying one CF gene affects the body's ability to fight off respiratory infections.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If this study finds differences, it could help explain why some people get more severe respiratory infections and point toward new ways to prevent or treat them.
What could go wrong
This is an observational study, not a treatment trial. It is small and early, so any findings will need much more research before they could lead to practical changes.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for RESPIRATORY INFECTIONS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
University of Iowa Hospitals and Clinics
RECRUITINGIowa City, Iowa, 52242, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••