Double immune attack: new combo therapy targets Hard-to-Treat head and neck cancers

NCT ID NCT01468896

First seen Mar 28, 2026 · Last updated May 01, 2026 · Updated 4 times

Summary

This study tested a combination of two drugs—cetuximab and interleukin-12—in 23 people with head and neck cancer that had spread, returned, or could not be surgically removed. The goal was to find the safest dose of interleukin-12 when given with cetuximab and to see if the pair could shrink tumors. The approach aims to boost the body's immune system to better fight the cancer.

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Contacts and locations

Locations

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.