Could a simple cervical swab replace biopsy for endometrial cancer detection?

NCT ID NCT07298707

First seen Jan 05, 2026 · Last updated Jun 01, 2026 · Updated 19 times

Summary

This study tests a new DNA-based test (CISENDO) on cells from a routine cervical smear to see if it can accurately detect endometrial cancer or precancerous lesions. About 3,500 women at medium-to-high risk will provide a cervical sample and then undergo standard hysteroscopy with biopsy for comparison. Some participants will be followed for up to a year to see if the test can also track how lesions change over time.

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