Brain oxygen monitor shows promise in protecting preterm infants from injury

NCT ID NCT06729398

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether using a brain oxygen monitor (cerebral NIRS) along with a treatment guideline could prevent brain injury in very low birth weight preterm infants. 129 babies born at 32 weeks or earlier or weighing under 1500 grams took part. The monitor was placed on the baby's head for the first 72 hours of life, and doctors followed a guideline to keep oxygen levels normal. The goal was to see if this approach reduced brain bleeding or white matter damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Near Infrared Spectroscopy (NIRS) device and SafeboosC treatment guideline

What this could lead to

If effective, this monitoring approach could help prevent brain injury and reduce mortality in fragile preterm infants.

What could go wrong

This is a single completed trial with 129 participants, so results may not apply broadly. The device only monitors oxygen levels and does not directly treat injury.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

periventricular leukomalacia brain injury prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dr. Cipto Mangunkusumo General Hospital

    Jakarta, Indonesia