New MRI clue could slash MS misdiagnosis rates
NCT ID NCT04495556
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 28 times
Summary
This study tests whether a specific brain MRI feature called the central vein sign can improve the accuracy of multiple sclerosis (MS) diagnosis. About 1 in 5 people diagnosed with MS are later found not to have it, leading to unnecessary and risky treatments. Researchers will scan 420 adults with typical or unusual symptoms to see if this sign helps tell MS apart from other conditions.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
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Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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Johns Hopkins University
Baltimore, Maryland, 21218, United States
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St. Michael's Hospital of Unity Health Toronto
Toronto, Ontario, M5B1W8, Canada
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The University of Texas at Austin
Austin, Texas, 78759, United States
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University of Colorado
Aurora, Colorado, 80045, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Southern California
Los Angeles, California, 90089, United States
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University of Vermont
Burlington, Vermont, 05405, United States
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Washington University in St. Louis
St Louis, Missouri, 63130, United States
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Yale University
New Haven, Connecticut, 06520, United States
Conditions
Explore the condition pages connected to this study.