Can bone cement stop spine fractures after cancer radiation? new trial aims to find out
NCT ID NCT02387905
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether injecting bone cement into the spine can prevent fractures after high-dose radiation treatment for cancer that has spread to the backbone. About 87 patients with solid tumors and spinal metastases will receive either standard radiation alone or radiation plus cement augmentation. The main goal is to see if the cement reduces the rate of vertebral fractures at 3 months, and also whether it lessens pain and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- bone cement (polymethylmethacrylate) injected into the vertebra
- What this could lead to
- If it works, this procedure could become a standard way to prevent painful spine fractures in cancer patients undergoing radiation, reducing the need for further surgery.
- What could go wrong
- This is a small Phase 2 trial with only 87 participants, so results may not apply to everyone. The procedure itself carries risks like cement leakage or infection, and it is not yet proven to prevent fractures long-term.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
M D Anderson Cancer Center
Houston, Texas, 77030, United States
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