New mammogram technique could spare thousands from unneeded breast biopsies

NCT ID NCT05206331

Recruiting now Diagnosis Sponsor: Margarita Louise Zuley Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether contrast-enhanced mammography (CEM) can safely reduce the number of breast biopsies for women with breast findings that are suspicious but not highly suspicious (BI-RADS 4A or 4B). About 2,100 women scheduled for a biopsy will first get a CEM. The goal is to see if CEM can correctly identify benign lesions and avoid at least 20% of unnecessary biopsies while still catching nearly all cancers.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

UPMC Magee-Womens Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••