Experimental cell therapy aims to stop deadly transplant complication

NCT ID NCT04328714

Summary

This early-stage study tested whether specially prepared stem cells could safely prevent graft-versus-host disease (GVHD) in patients receiving bone marrow transplants for blood cancers. GVHD is a serious and common complication where the donor's immune cells attack the patient's body. Researchers gave patients these modified cells around the time of transplant to try to calm the immune system and reduce GVHD risk. The study was terminated early after enrolling only 4 participants.

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Contacts and locations

Locations

  • Children's Healthcare of Atlanta at Egleston

    Atlanta, Georgia, 30322, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Winship Cancer Institute of Emory University

    Atlanta, Georgia, 30322, United States

Conditions

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