Engineered immune cells take aim at childhood blood cancers

NCT ID NCT06326463

First seen Jan 21, 2026 · Last updated Apr 28, 2026 · Updated 20 times

Summary

This early-phase study tests a new treatment called CD70-CAR T-cells for children and young adults (up to age 21) with blood cancers like leukemia, lymphoma, or MDS that have returned or not responded to standard therapy. The treatment involves taking the patient's own immune cells, modifying them in a lab to recognize and attack cancer cells that carry a protein called CD70, and giving them back through an IV. The main goals are to find the safest dose and see if the cells can reduce or eliminate the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.