Supercharged immune cells take on hard-to-treat lung cancer
NCT ID NCT05681780
First seen Dec 09, 2025 · Last updated Apr 24, 2026 · Updated 25 times
Summary
This early-stage trial tests a special immune cell therapy (CD40L TIL) combined with the drug nivolumab for people with advanced non-small cell lung cancer that has specific gene changes (EGFR, ALK, ROS1, or HER2). About 20 adults whose cancer worsened after standard treatments will receive their own lab-enhanced tumor-fighting cells. The main goal is to check safety, and researchers will also measure how well the tumors shrink.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact
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Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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