Supercharged immune cells take on advanced melanoma in new trial

NCT ID NCT06961357

First seen Nov 12, 2025 · Last updated Jun 13, 2026 · Updated 25 times

Summary

This study tests a new treatment for advanced melanoma that uses a patient's own immune cells, called TIL, which are boosted with a protein called CD40L to help them fight cancer better. About 36 people with different types of advanced melanoma that did not respond to standard treatments will receive these enhanced cells after a short course of chemotherapy. The goal is to see if this approach can shrink tumors and how safe it is.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

Conditions

Explore the condition pages connected to this study.