Supercharged immune cells take on advanced melanoma in new trial

NCT ID NCT06961357

First seen Nov 12, 2025 · Last updated Apr 26, 2026 · Updated 20 times

Summary

This study tests whether immune cells taken from a patient's own tumor and boosted with a molecule called CD40L can shrink advanced melanoma. About 36 people with melanoma that has spread or cannot be removed, and who have not responded to standard treatments, will take part. Participants first receive chemotherapy to prepare their immune system, then a single infusion of the boosted cells, followed by a short course of interleukin-2 to support the cells.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MELANOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

Conditions

Explore the condition pages connected to this study.