Gut bacteria boosts cancer therapy? new combo trial for kidney cancer

NCT ID NCT05122546

First seen Jan 11, 2026 · Last updated May 13, 2026 · Updated 17 times

Summary

This early-phase study tests whether adding a gut bacteria supplement (CBM588) to standard cancer drugs (nivolumab and cabozantinib) can improve treatment for advanced kidney cancer. About 31 adults with metastatic kidney cancer will take the supplement alongside their regular therapy. The goal is to see if the supplement changes the gut microbiome and possibly helps the immune system fight the cancer better.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.