Brain scans may reveal why behavioral therapy helps some teens with tics

NCT ID NCT06194305

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This study tests whether a structured behavioral therapy called CBIT can help children and teens aged 10–17 with chronic tics (Tourette syndrome or persistent tic disorder) gain better control over their symptoms. Participants receive 8 weekly CBIT sessions, learning to replace tics with competing movements. Researchers use brain scans and behavioral tracking to see who responds best and why.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Comprehensive Behavioral Intervention for Tics (CBIT), a manualized therapy teaching tic management skills through competing response training
What this could lead to
If successful, this could identify which children benefit most from CBIT and refine therapy to improve tic control and quality of life.
What could go wrong
This is a small Phase 2 study without a placebo group, so results may not prove CBIT works better than no treatment. Benefits may vary widely among participants.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California

    RECRUITING

    San Diego, California, 92093, United States

    Contact Email: •••••@•••••

    Contact

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55414, United States

    Contact

    Contact Email: •••••@•••••

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