CBD shows promise for traumatic brain injury recovery in small trial

NCT ID NCT05632627

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether cannabidiol (CBD) can improve thinking, mood, and other symptoms in people who have had a traumatic brain injury (TBI). 43 adults with mild or moderate TBI took either CBD or a placebo for 12 weeks. Researchers measured changes in cognition, neuropsychiatric symptoms, and inflammation markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cannabidiol (CBD)
What this could lead to
If it works, CBD could become a treatment option for lingering symptoms like memory problems, anxiety, and pain after a traumatic brain injury.
What could go wrong
This is a small, early-phase trial with only 43 people. The results may not apply to everyone, and CBD might not work better than a placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Colorado Anschutz

    Aurora, Colorado, 80045, United States

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