Could CBD ease anxiety in bipolar disorder? new trial aims to find out
NCT ID NCT05457465
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial is testing a custom, THC-free CBD product to see if it can reduce anxiety and depression in people with bipolar disorder. Twenty-five adults with bipolar I or II who have at least moderate anxiety will take the CBD daily for 4 weeks. Researchers will measure changes in anxiety and depression using standard rating scales.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cannabidiol (CBD)
What this could lead to
If it works, this could point toward a new option for managing anxiety and depression in people with bipolar disorder.
What could go wrong
This is a small, early-phase open-label trial with no placebo group, so results may not be reliable. CBD may also cause side effects like drowsiness or interactions with other medications.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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McLean Hospital
RECRUITINGBelmont, Massachusetts, 02478, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••