Yale scans brains of synthetic pot users to uncover addiction clues
NCT ID NCT03539575
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This observational study at Yale uses PET brain scans to measure CB1 receptor availability in 15 people who currently use synthetic cannabinoids. Researchers want to see if these receptors are lower in users and how that relates to thinking skills and brain rhythms during withdrawal. No treatment is given; it is purely a measurement study.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- [11-C]OMAR (a radioactive tracer used for PET scans)
- What this could lead to
- If successful, this could help explain how synthetic cannabinoids affect the brain and inform future treatments for dependence.
- What could go wrong
- This is a very small observational study (15 people) with no treatment being tested. It only measures brain changes, so it cannot directly lead to a new therapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Connecticut Mental Health Center
New Haven, Connecticut, 06519, United States
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