Real-World study shows cariprazine eases depression in bipolar i patients

NCT ID NCT06256367

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 25 times

Summary

This study followed 120 adults with bipolar I disorder who were starting cariprazine (Vraylar) for a depressive episode. Researchers measured changes in depression symptoms, daily functioning, and quality of life over 24 weeks in routine clinic visits. The goal was to see how well the medication works outside of strict trial conditions.

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Contacts and locations

Locations

  • Betts Psychiatric, PC /ID# 259737

    Eugene, Oregon, 97401-6008, United States

  • Bowman Medical Group /ID# 259989

    Beverly Hills, California, 90212-1910, United States

  • Chatham-Kent Clinical Trials /ID# 262414

    Chatham, Ontario, N7L 1C1, Canada

  • Clinique Woodward /ID# 264050

    Sherbrooke, Quebec, J1G 2N5, Canada

  • Douglas Mental Health University Institute /ID# 262048

    Verdun, Quebec, H4H 1R2, Canada

  • Georgia Psychiatric Consultants & Advanced Discovery Research /ID# 259975

    Atlanta, Georgia, 30318-3102, United States

  • Grand River Hospital /ID# 263962

    Kitchener, Ontario, N2G 1G3, Canada

  • Institut universitaire en santé mentale de Montréal /ID# 264665

    Montreal, Quebec, H1N 3M5, Canada

  • Montano Wellness LLC /ID# 259837

    Cromwell, Connecticut, 06416, United States

  • North Star Medical Research LL /ID# 259730

    Middleburg Heights, Ohio, 44130, United States

  • Omaha Insomnia and Psychiatric Services /ID# 259961

    Omaha, Nebraska, 68144-2359, United States

  • Quest Therapeutics of Avon /ID# 259838

    Avon Lake, Ohio, 44012-1004, United States

  • Rivus Wellness And Research Institute /ID# 259966

    Oklahoma City, Oklahoma, 73112, United States

  • START Clinic for Mood and Anxiety Disorders /ID# 262416

    Toronto, Ontario, M4W 2N4, Canada

  • Southlake Regional Health Centre /ID# 264212

    Newmarket, Ontario, L3Y 2P9, Canada

  • Sunny Johnson Medical Research Associates /ID# 267713

    Mississauga, Ontario, L5M 4N4, Canada

  • UC Davis /ID# 259723

    Sacramento, California, 95817-2310, United States

  • University of Alabama at Birmingham - Main /ID# 260000

    Birmingham, Alabama, 35233, United States

  • Ut Southwestern Medical Center /Parkland Health and Hospital System /Id# 260001

    Dallas, Texas, 75235-7709, United States

Conditions

Explore the condition pages connected to this study.