Real-World study shows cariprazine eases depression in bipolar i patients

NCT ID NCT06256367

Completed Symptom relief Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed 120 adults with bipolar I disorder who were having a major depressive episode and starting cariprazine (Vraylar). Researchers measured changes in depression symptoms, daily functioning, and quality of life over 24 weeks in a real-world clinic setting. The goal was to see how well the medication works outside of strict clinical trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

bipolar I disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIPOLAR I DISORDER

Contacts and locations

Locations

Betts Psychiatric, PC /ID# 259737

Eugene, Oregon, 97401-6008, United States
Bowman Medical Group /ID# 259989

Beverly Hills, California, 90212-1910, United States
Chatham-Kent Clinical Trials /ID# 262414

Chatham, Ontario, N7L 1C1, Canada
Clinique Woodward /ID# 264050

Sherbrooke, Quebec, J1G 2N5, Canada
Douglas Mental Health University Institute /ID# 262048

Verdun, Quebec, H4H 1R2, Canada
Georgia Psychiatric Consultants & Advanced Discovery Research /ID# 259975

Atlanta, Georgia, 30318-3102, United States
Grand River Hospital /ID# 263962

Kitchener, Ontario, N2G 1G3, Canada
Institut universitaire en santé mentale de Montréal /ID# 264665

Montreal, Quebec, H1N 3M5, Canada
Montano Wellness LLC /ID# 259837

Cromwell, Connecticut, 06416, United States
North Star Medical Research LL /ID# 259730

Middleburg Heights, Ohio, 44130, United States
Omaha Insomnia and Psychiatric Services /ID# 259961

Omaha, Nebraska, 68144-2359, United States
Quest Therapeutics of Avon /ID# 259838

Avon Lake, Ohio, 44012-1004, United States
Rivus Wellness And Research Institute /ID# 259966

Oklahoma City, Oklahoma, 73112, United States
START Clinic for Mood and Anxiety Disorders /ID# 262416

Toronto, Ontario, M4W 2N4, Canada
Southlake Regional Health Centre /ID# 264212

Newmarket, Ontario, L3Y 2P9, Canada
Sunny Johnson Medical Research Associates /ID# 267713

Mississauga, Ontario, L5M 4N4, Canada
UC Davis /ID# 259723

Sacramento, California, 95817-2310, United States
University of Alabama at Birmingham - Main /ID# 260000

Birmingham, Alabama, 35233, United States
Ut Southwestern Medical Center /Parkland Health and Hospital System /Id# 260001

Dallas, Texas, 75235-7709, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.