A 5-minute quiz might predict who gets severe chemo side effects

NCT ID NCT06717178

First seen Aug 18, 2026 ยท Last updated Aug 18, 2026

Summary

This study looks at whether a short risk-assessment tool, called the CARG score, can predict severe side effects from chemotherapy in cancer patients aged 70 and older. Participants will answer questions about their health and daily function before starting a new chemotherapy regimen. Researchers will then track hospitalizations, dose reductions, and treatment interruptions to see if the score matches real-world outcomes. The goal is to help doctors tailor chemotherapy plans to reduce harm in older adults.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Chemotherapy (a new chemotherapy regimen, either initial or changed)
What this could lead to
If the CARG score works well, it could help doctors predict which older patients are at higher risk of severe side effects, allowing safer, more personalized chemotherapy plans.
What could go wrong
This is an observational study, not a treatment trial, so it won't change outcomes directly. The score may not predict accurately in Chinese patients, and results depend on how well patients report symptoms.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450003, China

  • Renji Hospital

    Shanghai, Shanghai Municipality, 200127, China

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