Major study aims to uncover hidden heart disease and test steroid treatment

NCT ID NCT01477359

Recruiting now Knowledge-focused Sponsor: Ottawa Heart Institute Research Corporation Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is tracking 1,500 people with cardiac sarcoidosis—a condition where inflammation affects the heart—to learn how doctors currently diagnose and treat it. Researchers will also test whether corticosteroid therapy improves outcomes. The goal is to create better guidelines and reduce deaths from this often-missed disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: corticosteroids
What this could lead to: If successful, this study could provide clear guidelines for diagnosing and treating cardiac sarcoidosis, potentially reducing deaths and heart complications.
What could go wrong: This is an observational registry with a planned randomized trial; results are years away and may not change practice if the trial fails to show benefit or has low enrollment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiac sarcoidosis sarcoidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC SARCOIDOSIS

Contacts and locations

Locations

Centre Hospitalier de l"Universite de Montreal-Hotel Dieu
NOT_YET_RECRUITING

Montreal, Quebec, H2W 1T8, Canada
Hamilton Health Sciences Centre
RECRUITING

Hamilton, Ontario, L8L 2X2, Canada
Hokkaido University
RECRUITING

Sapporo, 060-8638, Japan
Libin Cardiovascular Institute of Alberta
RECRUITING

Calgary, Alberta, T2N 2T9, Canada
London Health Sciences Centre
RECRUITING

London, Ontario, N6A 5A5, Canada
McGill University Health Centre
RECRUITING

Montreal, Quebec, H3G 1A4, Canada
Montreal Heart Institute
RECRUITING

Montreal, Quebec, H1T 1C8, Canada
Prairie Vascular Research Inc-Regina General Hospital
RECRUITING

Regina, Saskatchewan, S4P 0W5, Canada
QEII Health Sciences Center
RECRUITING

Halifax, Nova Scotia, B3H 3A7, Canada
Southlake Regional Health Centre
RECRUITING

Newmarket, Ontario, L3Y 2P9, Canada
St. Paul's Hospital
RECRUITING

Vancouver, British Columbia, V5Z 1M9, Canada
Toronto General Hospital
RECRUITING

Toronto, Ontario, M5G 2C4, Canada
University of Alberta Hospital
RECRUITING

Edmonton, Alberta, T6G 2B7, Canada
University of Ottawa Heart Institute
RECRUITING

Ottawa, Ontario, K1Y 4W7, Canada

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