New drug combo shows promise in tough breast cancer

NCT ID NCT03414684

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 27 times

Summary

This study tests whether adding the immunotherapy drug nivolumab to standard chemotherapy (carboplatin) helps people with metastatic triple-negative breast cancer live longer without their disease getting worse. About 78 participants with advanced breast cancer that has spread will receive either carboplatin alone or carboplatin plus nivolumab. The main goal is to see if the combination improves progression-free survival.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02115, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Medical Center

    Milford, Massachusetts, 01757, United States

  • Dana-Farber/Brigham and Women's Cancer Center in clinical affiliation with South Shore Hospital

    South Weymouth, Massachusetts, 02190, United States

  • Dana-Farber/New Hampshire Oncology-Hematology

    Londonderry, New Hampshire, 03053, United States

  • Eastern Maine Medical Center

    Bangor, Maine, 04401, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • St. Elizabeth's Medical Center

    Boston, Massachusetts, 02135, United States

  • The Stamford Hospital

    Stamford, Connecticut, 06904, United States

  • University of Vermont Medical Center

    Burlington, Vermont, 05401, United States

Conditions

Explore the condition pages connected to this study.