Can a sugary drink before surgery steady blood sugar in diabetes?
NCT ID NCT07830537
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers are testing whether a carbohydrate drink before gastrointestinal surgery can reduce insulin resistance and improve blood sugar stability in adults with type 2 diabetes. Participants are randomly assigned to one of three groups: standard fasting without a carb drink, an oral maltodextrin drink, or intravenous glucose. The trial measures insulin resistance on the first day after surgery and tracks blood sugar levels, recovery, and safety events like hypoglycemia.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a carbohydrate drink made from maltodextrin, given before surgery
- What this could lead to
- If it works, a simple carbohydrate drink before surgery could become a routine step that helps people with type 2 diabetes recover with steadier blood sugar and less insulin resistance.
- What could go wrong
- This is a single-center study of 126 people, so the results may not apply everywhere. The drink could also raise blood sugar too high or cause reflux in some patients, which the trial monitors closely.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 126 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 1.Age 18 to 75 years, regardless of sex. 2.Diagnosis of type 2 diabetes mellitus. 3.Glycated hemoglobin (HbA1c) ≤8.0%, with preoperative fasting plasma glucose generally ≤10.0 mmol/L. 4.Scheduled to undergo elective gastrointestinal surgery. 5.Able to wear a continuous glucose monitoring (CGM) device for at least 24 hours before surgery and willing to continue monitoring until hospital discharge or the protocol-specified time point. 6.Able to understand the study procedures, voluntarily participate in the study, and provide written informed consent. Exclusion Criteria: * 1\. Known or highly suspected diabetic gastroparesis, delayed gastric emptying, gastric outlet obstruction, or upper gastrointestinal obstruction. 2\. Severe gastroesophageal reflux disease or other conditions considered by the investigator to confer a high risk of aspiration. 3\. Emergency surgery or other non-elective surgery for which the study intervention cannot be implemented as planned. 4\. Type 1 diabetes mellitus, gestational diabetes mellitus, or other specific types of diabetes. 5\. Pregnancy or breastfeeding. 6. Recent systemic glucocorticoid therapy. 7. Severe hepatic or renal dysfunction, or active severe infection. 8. Inability to comply with CGM use, cognitive or psychiatric conditions preventing completion of study assessments, or anticipated poor adherence to the study protocol. 9\. Any other condition that, in the investigator's judgment, makes the participant unsuitable for enrollment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
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