Ankle glide vs. standard exercise: which helps diabetic stiffness?

NCT ID NCT07827625

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Recruiting now This study
This trial is taking on new participants right now.
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Registered, but not yet taking participants.
By invitation only
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Running, but no longer taking on new participants.
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Cancelled before anyone took part.

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Approved
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When the status isn't known

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First seen Sep 18, 2026 · Last updated Sep 18, 2026

Summary

People with type 2 diabetes often develop stiff ankles, pain, and walking problems. This trial compares two physiotherapy approaches: Mulligan Mobilization with Movement, where a therapist applies a gentle glide to the ankle during active movement, and conventional physiotherapy with range-of-motion exercises, calf raises, and stretching. Researchers will enroll 56 adults aged 50 to 70 who have had diabetes for more than five years and assign them randomly to one of the two programs for six weeks. The study measures changes in pain, ankle range of motion, walking speed, and quality of life to see which method works better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mulligan Mobilization with Movement, a hands-on physiotherapy technique that applies a gentle sustained glide to the ankle while the patient actively moves it
What this could lead to
If it works, this could give physiotherapists a clearer reason to choose one ankle technique over another for people with type 2 diabetes, potentially improving walking and comfort.
What could go wrong
The trial is small, with 56 participants, and lasts only six weeks, so any benefits may be modest or fade. Manual therapy can cause temporary soreness, and results may not apply to everyone with diabetes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 56 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 50-70 years * Both male and female * Diabetes Mellitus \> 5 years' duration * Willing to participate and provide informed consent * Pain rated between 3-7 on the Numeric Pain Rating Scale (NPRS) * Ankle dorsiflexion range of motion ≤10° on goniometric assessment Exclusion Criteria: * History of recent lower-limb surgery, fracture, or dislocation (\<6 months) * Active diabetic foot ulcer or Charcot foot * Any inflammatory joint disease (e.g., rheumatoid arthritis) * Congenital foot deformity * Diagnosed diabetic peripheral neuropathy

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

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  2. The official record

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Contacts and locations

Locations

  • Ibadat International University

    RECRUITING

    Islamabad, Federal, 47000, Pakistan

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