New CAR-T therapy takes on tough rheumatoid arthritis in Head-to-Head trial

NCT ID NCT06475495

First seen Mar 17, 2026 · Last updated May 16, 2026 · Updated 6 times

Summary

This study tests a new treatment called CAR-T cell therapy against a standard drug, rituximab, in people with active rheumatoid arthritis that hasn't improved with other treatments. The goal is to see if CAR-T cells are safe and can reduce harmful antibodies linked to the disease. Thirteen participants will receive either a single dose of CAR-T cells or two doses of rituximab, and be followed for one year.

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Contacts and locations

Locations

  • Charité - Universitätsmedizin Berlin

    Berlin, State of Berlin, 10117, Germany

Conditions

Explore the condition pages connected to this study.