Blood test may predict who benefits from CAR-T for lymphoma

NCT ID NCT06352242

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a blood test can predict how well CAR-T cell therapy works in people with diffuse large B-cell lymphoma. Researchers will take blood samples before and after treatment to look for a specific immune cell activity called trogocytosis. The goal is to find a pattern that tells doctors early on if the therapy is likely to succeed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test that helps doctors predict which patients will respond well to CAR-T therapy for lymphoma.

What could go wrong

This is an early observational study, not a treatment trial. It may not find a reliable predictive signature, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Investigation Center, University Hospital

    RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clinical hematology department, University Hospital

    RECRUITING

    Montpellier, France

    Contact Email: •••••@•••••