Scientists test revolutionary immune cell therapy for debilitating muscle disease

NCT ID NCT06626919

Summary

This is an early-stage safety study testing a new type of treatment called anito-cel for adults with generalized myasthenia gravis, a chronic autoimmune disease that causes severe muscle weakness. The therapy involves collecting a patient's own immune cells, genetically modifying them to target a specific protein (BCMA) involved in the disease, and infusing them back. The main goals are to find a safe dose and see if this one-time treatment can reduce disease symptoms and improve daily function.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10032, United States

  • Houston Methodist Hospital

    RECRUITING

    Houston, Texas, 77030, United States

  • Karmanos Cancer Institute

    RECRUITING

    Detroit, Michigan, 48201, United States

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43221, United States

  • Oregon Health & Science University (OHSU)

    RECRUITING

    Portland, Oregon, 97239, United States

  • Stanford Hospital

    RECRUITING

    Palo Alto, California, 94305, United States

  • Temple University Hospital

    RECRUITING

    Philadelphia, Pennsylvania, 19140, United States

  • UCLA Medical Center

    RECRUITING

    Los Angeles, California, 90095, United States

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

  • University of California, Irvine

    RECRUITING

    Orange, California, 92602, United States

  • University of Minnesota Delaware Clinical Research Unit

    RECRUITING

    Minneapolis, Minnesota, 55414, United States

  • University of South Florida - Carol and Frank Morsani Center of Advanced Healthcare

    RECRUITING

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.