Could CAR-T cells tame tough scleroderma in kids?
NCT ID NCT06792344
First seen Jan 05, 2026 · Last updated May 13, 2026 · Updated 21 times
Summary
This early-phase study tests a new treatment for children with severe systemic sclerosis (scleroderma) that hasn't responded to standard drugs. Doctors will give patients a single infusion of their own immune cells that have been reprogrammed to target and destroy faulty B cells. The main goal is to see if the treatment is safe and if it can improve skin stiffness and overall disease activity over six months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 0571, China
Contact
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Children's Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310053, Christmas Island
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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