Engineered immune cells take on rare Muscle-Weakening disease

NCT ID NCT06371040

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 28 times

Summary

This early-stage study tests a new treatment called CD19-BCMA CAR-T for people with refractory generalized myasthenia gravis, a condition where the immune system attacks nerve-muscle connections, causing severe weakness. The therapy uses a patient's own immune cells, modified to target and destroy faulty immune cells. The main goal is to find a safe dose and check for side effects in about 9 to 12 adults.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tangdu Hospital, The Fourth Military Medical University

    RECRUITING

    Xi'an, Shaanxi, 710038, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.