Scientists re-engineer Kids' own cells to hunt deadly brain tumors
NCT ID NCT04903080
Summary
This early-stage trial is testing a new personalized treatment for children with ependymoma, a type of brain tumor that has come back or stopped responding to standard care. Doctors take a child's own immune cells, modify them in a lab to recognize and attack the tumor, and then infuse them back into the patient. The main goals are to see if this approach is safe and practical to deliver across multiple hospitals.
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Contacts and locations
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Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30329, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90026, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Pittsburgh Children's Hospital of UPMC
Pittsburgh, Pennsylvania, 15224, United States
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Texas Children's Cancer Center
Houston, Texas, 77030, United States
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The Hospital for Sick Children
Toronto, Ontario, M5G1X8, Canada
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University of Florida
Gainesville, Florida, 32608, United States
Conditions
Explore the condition pages connected to this study.