Experimental cell therapy aims to calm transplant rejection
NCT ID NCT05993611
Summary
This early-stage trial is testing a new cell therapy for patients with chronic graft-versus-host disease (cGVHD), a serious complication where donor immune cells attack the patient's body after a bone marrow transplant. Researchers modify a donor's immune cells in the lab to create 'regulatory' cells designed to calm this harmful immune attack. The study will first check if this treatment is safe and determine the right dose for 27 adult patients whose cGVHD hasn't responded well to steroids.
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Contacts and locations
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Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
Conditions
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