Experimental CAR T-Cell therapy takes on tough lupus cases
NCT ID NCT06984341
First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 30 times
Summary
This early-stage study tests a new treatment called P-CD19CD20-ALLO1 for people with severe lupus that hasn't improved with standard therapies. The treatment uses specially engineered immune cells to target and reduce harmful B cells. The study involves 162 adults aged 18-75 and will check for safety, side effects, and how well the therapy controls lupus activity.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Alabama at Birmingham: The Kirklin Clinic
Birmingham, Alabama, 35233, United States
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University of Iowa
Iowa City, Iowa, 52242, United States
Conditions
Explore the condition pages connected to this study.