Donor immune cells show promise against returning blood cancers
NCT ID NCT02050347
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a new treatment for people with certain blood cancers (lymphoma or leukemia) that have returned after a stem cell transplant. Researchers take immune cells called T cells from the original stem cell donor, modify them to recognize and attack cancer cells (using a special receptor called CAR), and give them to the patient. The main goals are to find the safest dose and to see if this approach can control the cancer without causing severe side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for B CELL ALL are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Houston Methodist Hospital
Houston, Texas, 77030, United States
-
Texas Children's Hospital
Houston, Texas, 77030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Supercharged immune cells take aim at cancer and viruses in one shot
- Engineered t cells with a kill switch aim to make stem cell transplants safer
- Gut bacteria may hold key to chemo side effects
- New 'In-Body' CAR-T therapy takes aim at Hard-to-Treat lymphoma
- Experimental 'In-Situ' vaccine aims to train immune system against three cancers
- Scientists hunt for lymphoma genes in families with multiple cases