New study aims to tame dangerous immune reactions from cancer therapy

NCT ID NCT05306080

First seen Mar 18, 2026 · Last updated Apr 26, 2026 · Updated 5 times

Summary

This early-phase study tests whether certain drugs can safely and effectively treat severe side effects (cytokine release syndrome and HLH-like syndrome) that can occur after CAR T cell therapy. About 10 adults already receiving CAR T cells for cancer will be given these rescue treatments if needed. The goal is to see if the approach is safe and feasible, not to cure the underlying disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HLH are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.