Immune cells engineered to hunt brain tumors enter first human test

NCT ID NCT07551336

First seen May 13, 2026 · Last updated May 15, 2026 · Updated 1 time

Summary

This early-phase trial tests a new treatment for adults with glioblastoma or other high-grade gliomas that have come back after standard therapy. The treatment uses specially engineered immune cells (CAR-NK cells) that are designed to target two different markers on tumor cells at once, which may help prevent the cancer from escaping. Participants will have their tumor tested to find the best two targets, then receive the cells directly into the brain. The main goals are to check safety and find the right dose.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University Shenzhen Hospital

    RECRUITING

    Shenzhen, Guangdong, 518036, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.