Supercharged immune cells take on deadly brain tumors
NCT ID NCT07551336
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tests a new treatment for people with recurrent glioblastoma, a fast-growing brain cancer. The treatment uses a patient's own immune cells (NK cells) that have been engineered in a lab to better recognize and attack tumor cells. The cells are delivered directly into the brain. The study aims to find a safe dose and see if the treatment can shrink tumors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Dual-targeting CAR-NK cells (immune cells engineered to recognize and attack brain tumor cells)
- What this could lead to
- If this works, it could point toward a new treatment option for people with recurrent glioblastoma, a type of brain cancer that is very hard to treat.
- What could go wrong
- This is a very early (phase 1) and small trial (36 people). The main goal is safety, not effectiveness. It may not work, and there are risks like severe immune reactions or brain swelling.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Peking University Shenzhen Hospital
RECRUITINGShenzhen, Guangdong, 518036, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a One-Two punch slow recurrent brain cancer?