Supercharged immune cells take on deadly brain tumors

NCT ID NCT07551336

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests a new treatment for people with recurrent glioblastoma, a fast-growing brain cancer. The treatment uses a patient's own immune cells (NK cells) that have been engineered in a lab to better recognize and attack tumor cells. The cells are delivered directly into the brain. The study aims to find a safe dose and see if the treatment can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dual-targeting CAR-NK cells (immune cells engineered to recognize and attack brain tumor cells)

What this could lead to

If this works, it could point toward a new treatment option for people with recurrent glioblastoma, a type of brain cancer that is very hard to treat.

What could go wrong

This is a very early (phase 1) and small trial (36 people). The main goal is safety, not effectiveness. It may not work, and there are risks like severe immune reactions or brain swelling.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

glioblastoma glioma malignant glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University Shenzhen Hospital

    RECRUITING

    Shenzhen, Guangdong, 518036, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••