Engineered immune cells take aim at Hard-to-Treat cancers
NCT ID NCT07510828
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tests a new treatment using donor immune cells (CAR-NK cells) that are engineered to recognize and attack cancer. The treatment is personalized based on a tumor's unique markers. It is for adults with advanced solid tumors that have not responded to other therapies. The goal is to see if it is safe and shows signs of shrinking tumors.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- CAR-NK cells (immune cells from a donor engineered to target cancer)
- What this could lead to
- If it works, this could point toward a new treatment option for people with advanced solid tumors that have stopped responding to standard therapies.
- What could go wrong
- This is an early-phase trial with only 60 participants, so the treatment may not work or could cause serious side effects. The approach is complex and may not be widely available.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Peking University Shenzhen Hospital
RECRUITINGShenzhen, Guangdong, 518036, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a dual protein blocker shrink Hard-to-Treat tumors?
- Can a new biologic boost the immune System's fight against advanced tumors?
- Experimental pill SHY-ONC6 takes on Hard-to-Treat cancers
- Experimental pill takes on advanced cancers alongside immunotherapy
- Smart T-Cell engager aims to outsmart tumors in first human test