Pepper patch could ease tailbone pain without pills

NCT ID NCT06023706

Recruiting now Symptom relief Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a high-dose capsaicin patch (made from chili pepper extract) can reduce chronic tailbone pain (coccygodynia) better than a low-dose patch. About 188 adults with pain lasting over 3 months will receive either the 8% patch or a control patch applied once for one hour. The main goal is to see if more people report improvement after 60 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: capsaicin 8% patch (Qutenza)
What this could lead to: If it works, this could offer a new, non-drug option to reduce chronic tailbone pain, making sitting and daily activities more comfortable.
What could go wrong: This is a Phase 3 trial, but the effect may be modest or no better than a low-dose patch. Skin irritation or burning at the patch site is a known side effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coccygodynia neuralgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COCCYGODYNIA COCCYX DISORDER NEUROPATHIC PAIN

Contacts and locations

Locations

Brest University Hospital
RECRUITING

Brest, France
Confluent Private Hospital Centre
RECRUITING

Nantes, France
GH Paris saint Joseph
RECRUITING

Paris, France
Nantes University Hospital
RECRUITING

Nantes, France
Rouen University Hospital
RECRUITING

Rouen, France
Vendée Departmental Hospital
RECRUITING

La Roche-sur-Yon, France

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