Lung cancer drug trial stopped early — too few patients to know if it works

NCT ID NCT04926831

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested the drug capmatinib in people with early-stage non-small cell lung cancer that has a specific genetic change (MET mutation). The goal was to see if taking the drug before and after surgery could improve outcomes. However, the trial was stopped early after enrolling only 4 participants, so no meaningful conclusions can be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

capmatinib (a targeted cancer pill)

What this could lead to

If it worked, this could point toward a treatment that shrinks lung tumors before surgery and delays recurrence afterward.

What could go wrong

The trial was terminated early with only 4 participants, so we have very little data. It is unclear if capmatinib is effective or safe in this setting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fairfax Northern Virginia Hem Onc

    Fairfax, Virginia, 22031, United States

  • Fairfax Northern Virginia Hem Onc .

    Fairfax, Virginia, 22031, United States

  • UCLA Oncology Hematology

    La Jolla, California, 92037, United States

  • UCLA Oncology Hematology .

    La Jolla, California, 92037, United States

  • University of California Davis Cancer Center

    Sacramento, California, 95817, United States

  • University of California Davis Cancer Center .

    Sacramento, California, 95817, United States