New hope for advanced breast cancer: capivasertib combo trial launches
NCT ID NCT07281833
First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times
Summary
This phase 3 study tests whether adding capivasertib to standard hormone therapy helps people with HR+/HER2- advanced breast cancer stay on treatment longer and maintain quality of life. About 250 adults whose cancer worsened after prior hormone therapy will take capivasertib plus standard care and report their well-being via questionnaires. Results will be compared to historical data from a similar trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AGAPLESION Markus Krankenhaus
RECRUITINGFrankfurt, 60431, Germany
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Brustzentrum Niederrhein, Johanniter Bethesda Krankenhaus
RECRUITINGMönchengladbach, North Rhine-Westphalia, 41061, Germany
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Champalimaud Clinical Centre
RECRUITINGLisbon, 1400-038, Portugal
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Evanglisches Kliniken Essen Mitte
RECRUITINGEssen, 45136, Germany
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Gynäkologische Gemeinschaftspraxis-Ärztehaus am Bahnhofsplatz
RECRUITINGHildesheim, 31134, Germany
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Institut Jules Bordet
RECRUITINGAnderlecht, 1070, Belgium
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Kliniken der Stadt Köln gGmbH, Krankenhaus Holweide
RECRUITINGCologne, 51067, Germany
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Klinikum der Universität München
RECRUITINGMünchen, 80336, Germany
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MKS St. Paulus GmBH Mariankrankenhaus
RECRUITINGSchwerte, 58239, Germany
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MVZ Media Vita (St. Franziskus-Hospital Münster)
RECRUITINGMünster, 48145, Germany
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Mammazentrum Hamburg am Krankenhaus Jerusalem
RECRUITINGHamburg, 20357, Germany
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Rotkreuzkliniken München
RECRUITINGMünchen, 80637, Germany
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St. Elisabeth-Krankenhaus GmbH, Brustzentrum - Senologie
RECRUITINGCologne, North Rhine-Westphalia, 50935, Germany
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Universitätsklinikum Essen
RECRUITINGEssen, North Rhine-Westphalia, 45130, Germany
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Universitätsklinikum Münster AöR Brustzentrum
NOT_YET_RECRUITINGMünster, North Rhine-Westphalia, 48149, Germany
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Universitätsklinikum Ulm
RECRUITINGUlm, 89075, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a radioactive tracer pinpoint Cancer's first stop?
- Can a Two-Step drug combo outsmart advanced HER2-Positive breast cancer?
- Can a personalized exercise program boost recovery in cancer survivors?
- Smartwatch could spot nerve damage before it starts
- Could ionized gas help fight breast cancer after surgery?
- Radiation may let breast cancer patients keep their nipple