Can metformin protect the brains of young cannabis users with psychosis?

NCT ID NCT07001878

First seen Apr 09, 2026 · Last updated May 16, 2026 · Updated 4 times

Summary

This study looks at how high-potency cannabis affects the brain's white matter in young adults (ages 18-25) with early psychosis. Participants will take metformin daily for 6 months and undergo brain scans and questionnaires. The goal is to see if this approach is feasible for a larger trial, not to prove treatment effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nova Scotia Early Psychosis Program

    RECRUITING

    Halifax, Nova Scotia, Canada

  • Psychosis Intervention Early Recovery Program

    RECRUITING

    St. John's, Newfoundland and Labrador, Canada

Conditions

Explore the condition pages connected to this study.