New drug duo tested to fight spreading cancers

NCT ID NCT04609566

Completed Disease control Sponsor: Seagen, a wholly owned subsidiary of Pfizer Source: ClinicalTrials.gov ↗

Summary

This study tested whether combining two existing cancer drugs, brentuximab vedotin and pembrolizumab, could help treat several types of advanced cancer that had spread to other parts of the body. It involved 161 people with metastatic melanoma, non-small cell lung cancer, or head and neck cancer. The main goal was to see how well the combination shrank tumors and how long the benefit lasted, while carefully tracking side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Arizona Oncology Associates, PC - HOPE

Tucson, Arizona, 85704, United States
Arizona Oncology Associates, PC - HOPE

Tucson, Arizona, 85711, United States
Arizona Oncology Associates, PC - HOPE

Tucson, Arizona, 85745, United States
California Cancer Associates for Research and Excellence Inc (cCARE)

San Marcos, California, 92069, United States
California Cancer Associates for Research and Excellence, Inc (cCARE)

Encinitas, California, 92024, United States
California Cancer Associates for Research and Excellence, Inc. cCARE

Fresno, California, 93720, United States
Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute (SOCCI)

Los Angeles, California, 90048, United States
Clinical and Translational Research Center (CTRC)

Aurora, Colorado, 80045, United States
Fred Hutchinson Cancer Care Center

Seattle, Washington, 98109, United States
Highlands Oncology Group, PA

Fayetteville, Arkansas, 72703, United States
Highlands Oncology Group, PA

Rogers, Arkansas, 72758, United States
Highlands Oncology Group, PA

Springdale, Arkansas, 72762, United States
Inova Schar Cancer Institue Infusion Pharmacy

Fairfax, Virginia, 22031, United States
Inova Schar Cancer Institute

Fairfax, Virginia, 22031, United States
Massey Cancer Center Clinical & Translational Research Lab

Richmond, Virginia, 23298, United States
Minnesota Oncology Hematology PA

Burnsville, Minnesota, 55337, United States
Minnesota Oncology Hematology PA

Coon Rapids, Minnesota, 55433, United States
Minnesota Oncology Hematology PA

Edina, Minnesota, 55435, United States
Minnesota Oncology Hematology PA

Fridley, Minnesota, 55432, United States
Minnesota Oncology Hematology PA

Maple Grove, Minnesota, 55369, United States
Minnesota Oncology Hematology PA

Maplewood, Minnesota, 55109, United States
Minnesota Oncology Hematology PA

Minneapolis, Minnesota, 55404, United States
Minnesota Oncology Hematology PA

Plymouth, Minnesota, 55441, United States
Minnesota Oncology Hematology PA

Saint Paul, Minnesota, 55102, United States
Minnesota Oncology Hematology PA

Woodbury, Minnesota, 55125, United States
Nebraska Medicine

Omaha, Nebraska, 68105, United States
Nebraska Medicine - Bellevue Medical Center

Bellevue, Nebraska, 68123, United States
Nebraska Medicine - Village Pointe

Omaha, Nebraska, 68118, United States
New York Oncology Hematology, P.C.

Albany, New York, 12206, United States
New York Oncology Hematology, P.C.

Albany, New York, 12208, United States
New York Oncology Hematology, P.C.

Clifton Park, New York, 12065, United States
Northwestern Medical Group

Chicago, Illinois, 60611, United States
Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States
Norton Audubon Hospital

Louisville, Kentucky, 40217, United States
Norton Brownsboro Hospital

Louisville, Kentucky, 40241, United States
Norton Cancer Institute Downtown

Louisville, Kentucky, 40202, United States
Norton Cancer Institute, Audubon Hospital Campus

Louisville, Kentucky, 40217, United States
Norton Cancer Institute, Brownsboro Hospital Campus

Louisville, Kentucky, 40241, United States
Norton Hospital

Louisville, Kentucky, 40202, United States
Oncology & Hematology Associates of Southwest Virginia Inc.

Low Moor, Virginia, 24457, United States
Oncology & Hematology Associates of Southwest Virginia, INC.

Wytheville, Virginia, 24382, United States
Oncology Associates of Oregon, P.C.

Eugene, Oregon, 97401, United States
Oncology Consultants, PA

Houston, Texas, 77024, United States
Oncology and Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care

Blacksburg, Virginia, 24060, United States
Oncology and Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care

Roanoke, Virginia, 24014, United States
Oncology and Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care

Salem, Virginia, 24153, United States
Oncology_Hematology Care Clinical Trials,LLC

Cincinnati, Ohio, 45211, United States
Oncology_Hematology Care Clinical Trials,LLC

Cincinnati, Ohio, 45236, United States
Oncology_Hematology Care Clinical Trials,LLC

Cincinnati, Ohio, 45242, United States
Oncology_Hematology Care Clinical Trials,LLC

Cincinnati, Ohio, 45245, United States
Oncology_Hematology Care Clinical Trials,LLC

Fairfield, Ohio, 45014, United States
Rocky Mountain Cancer Centers, LLP

Aurora, Colorado, 80012, United States
Rocky Mountain Cancer Centers, LLP

Boulder, Colorado, 80303, United States
Rocky Mountain Cancer Centers, LLP

Colorado Springs, Colorado, 80907, United States
Rocky Mountain Cancer Centers, LLP

Denver, Colorado, 80218, United States
Rocky Mountain Cancer Centers, LLP

Denver, Colorado, 80220, United States
Rocky Mountain Cancer Centers, LLP

Lakewood, Colorado, 80228, United States
Rocky Mountain Cancer Centers, LLP

Littleton, Colorado, 80120, United States
Rocky Mountain Cancer Centers, LLP

Lone Tree, Colorado, 80124, United States
Rocky Mountain Cancer Centers, LLP

Longmont, Colorado, 80504, United States
Rocky Mountain Cancer Centers, LLP

Pueblo, Colorado, 81003, United States
Rocky Mountain Cancer Centers, LLP

Thornton, Colorado, 80260, United States
Texas Oncology - Central South

Austin, Texas, 78705, United States
Texas Oncology - Central South (Balcones Dr)

Austin, Texas, 78731, United States
Texas Oncology - Central South (James Casey)

Austin, Texas, 78745, United States
Texas Oncology - Fort Worth Cancer Center

Fort Worth, Texas, 76104, United States
Texas Oncology-DFW

Dallas, Texas, 75246, United States
Texas Oncology-DFW

Fort Worth, Texas, 76104, United States
The Angeles Clinic And Research Institute, A Cedars-Sinai Affiliate

Los Angeles, California, 90025, United States
The Angeles Clinic and Research Institute, A Cedars-Sinai Affiliate (Emergency Back-Up Only)

Santa Monica, California, 90404, United States
The University of Kansas Cancer Center

Westwood, Kansas, 66205, United States
The University of Kansas Cancer Center, Investigational Drug Services

Westwood, Kansas, 66205, United States
Tissue and Data Acquisition and Analysis Core (TDAAC)

Richmond, Virginia, 23298, United States
Toledo Clinic Cancer Center

Toledo, Ohio, 43623, United States
US Oncology Investigational Product Center (IPC)

Irving, Texas, 75063, United States
US Oncology Investigational Products Center (IPC)

Irving, Texas, 75063, United States
University Of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of Colorado Hospital - Anschutz Inpatient Pavilion (AIP)

Aurora, Colorado, 80045, United States
University of Colorado Hospital - Anschutz Outpatient Pavilion (AOP)

Aurora, Colorado, 80045, United States
University of Colorado Hospital-Anschutz Cancer Pavilion (ACP)

Aurora, Colorado, 80045, United States
University of Kansas Medical Center

Kansas City, Kansas, 66160, United States
VCU Health Community Memorial Hospital

South Hill, Virginia, 23970, United States
VCU Health Stony Point

Richmond, Virginia, 23235, United States
VCU Health Tappahannock Hospital

Tappahannock, Virginia, 22560, United States
VCU Health- Adult Outpatient Pavilion (AOP) Investigational Drug Services

Richmond, Virginia, 23298, United States
Virginia Commonwealth University

Richmond, Virginia, 23298, United States
Virginia Commonwealth University Massey Cancer Center

Richmond, Virginia, 23219, United States
Virginia Oncology Associates

Chesapeake, Virginia, 23320, United States
Virginia Oncology Associates

Hampton, Virginia, 23666, United States
Virginia Oncology Associates

Newport News, Virginia, 23606, United States
Virginia Oncology Associates

Norfolk, Virginia, 23502, United States
Virginia Oncology Associates

Virginia Beach, Virginia, 23456, United States
Virginia Oncology Associates

Williamsburg, Virginia, 23188, United States

Conditions

Explore the condition pages connected to this study.

MELANOMA NON-SMALL CELL LUNG CANCER SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK