New cancer drug combo tested in major trial

NCT ID NCT03400332

Summary

This study tested the safety and effectiveness of an experimental drug called BMS-986253 when given alongside established immunotherapy drugs (nivolumab with or without ipilimumab). It involved 281 people with advanced, hard-to-treat cancers, including melanoma. The main goals were to find a safe dose and see if the combination could shrink tumors.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Comprehensive Cancer Centers Of Nevada

    Las Vegas, Nevada, 89169, United States

  • Local Institution - 0001

    Pittsburgh, Pennsylvania, 15213, United States

  • Local Institution - 0002

    New York, New York, 10032, United States

  • Local Institution - 0003

    Lutherville, Maryland, 21093, United States

  • Local Institution - 0004

    Ann Arbor, Michigan, 48109, United States

  • Local Institution - 0005

    Hackensack, New Jersey, 07601, United States

  • Local Institution - 0006

    San Antonio, Texas, 78240, United States

  • Local Institution - 0007

    Lakewood, Colorado, 80228, United States

  • Local Institution - 0008

    Norfolk, Virginia, 23502, United States

  • Local Institution - 0009

    Greenville, South Carolina, 29615, United States

  • Local Institution - 0010

    Dallas, Texas, 75246, United States

  • Local Institution - 0011

    Austin, Texas, 78705, United States

  • Local Institution - 0012

    Columbia, Maryland, 21044, United States

  • Local Institution - 0013

    Tyler, Texas, 75702, United States

  • Local Institution - 0014

    Fort Worth, Texas, 76104-3927, United States

  • Local Institution - 0015

    Fairfax, Virginia, 22031, United States

  • Local Institution - 0017

    Eugene, Oregon, 97401, United States

  • Local Institution - 0018

    Houston, Texas, 77030, United States

  • Local Institution - 0019

    Birmingham, West Midlands, B15 2TH, United Kingdom

  • Local Institution - 0020

    Toronto, Ontario, M5G 1Z5, Canada

  • Local Institution - 0021

    Pamplona, 31008, Spain

  • Local Institution - 0022

    Madrid, 28040, Spain

  • Local Institution - 0023

    Madrid, 28050, Spain

  • Local Institution - 0024

    Manchester, Greater Manchester, M20 4BX, United Kingdom

  • Local Institution - 0025

    New York, New York, 10029, United States

  • Local Institution - 0026

    Rozzano-milano, 20089, Italy

  • Local Institution - 0027

    Napoli, 80131, Italy

  • Local Institution - 0028

    Oklahoma City, Oklahoma, 73104, United States

  • Local Institution - 0029

    Vancouver, British Columbia, V5Z 4E6, Canada

  • Local Institution - 0030

    Edmonton, Alberta, T6G 1Z2, Canada

  • Local Institution - 0032

    New Brunswick, New Jersey, 08903, United States

  • Local Institution - 0034

    Berlin, 12200, Germany

  • Local Institution - 0036

    Ghent, 9000, Belgium

  • Local Institution - 0037

    Brussels, 1200, Belgium

  • Local Institution - 0039

    Zurich, 8091, Switzerland

  • Local Institution - 0040

    Lausanne, 1011, Switzerland

  • Local Institution - 0041

    Sankt Gallen, 9007, Switzerland

  • Local Institution - 0042

    Milan, 20132, Italy

  • Local Institution - 0043

    Forlì, 47014, Italy

  • Local Institution - 0044

    Málaga, 29010, Spain

  • Local Institution - 0045

    Madrid, 28034, Spain

  • Local Institution - 0047

    Santiago de Compostela, 15706, Spain

  • Local Institution - 0049

    Lund, 221 85, Sweden

  • Local Institution - 0052

    Mainz, Rhineland-Palatinate, 55131, Germany

  • Local Institution - 0053

    Hamburg, 20251, Germany

  • Local Institution - 0054

    Tübingen, Baden-Wurttemberg, 72076, Germany

  • Local Institution - 0055

    Toronto, Ontario, M5G 2M9, Canada

  • Local Institution - 0056

    Montreal, Quebec, H2X 0A9, Canada

  • Local Institution - 0058

    Salt Lake City, Utah, 84112, United States

  • Local Institution - 0059

    Springdale, Arkansas, 72762, United States

  • Local Institution - 0060

    Boston, Massachusetts, 02215, United States

  • Local Institution - 0067

    Marseille, Bouches-du-Rhône, 13385, France

  • Local Institution - 0068

    Paris, 75010, France

  • Local Institution - 0069

    Villejuif, 94800, France

  • Local Institution - 0071

    Krakow, 31-115, Poland

  • Local Institution - 0076

    Omaha, Nebraska, 68130, United States

  • Local Institution - 0077

    Warsaw, 02-781, Poland

  • Local Institution - 0078

    Victoria, British Columbia, V8R 6V5, Canada

  • Local Institution - 0082

    Kortrijk, 8500, Belgium

  • Local Institution - 0083

    Glasgow, Lanarkshire, G12 0YN, United Kingdom

  • Local Institution - 0085

    Nantes, 44000, France

  • Local Institution - 0087

    Atlanta, Georgia, 30322, United States

  • Local Institution - 0088

    Wollstonecraft, New South Wales, 2065, Australia

  • Local Institution - 0090

    Melbourne, Victoria, 3000, Australia

  • Local Institution - 0091

    Ballarat Central, VIC 3350, Australia

  • Local Institution - 0095

    Melbourne, Victoria, 3004, Australia

  • Local Institution - 0096

    Adelaide, South Australia, 5000, Australia

  • Local Institution - 0097

    Perth, Western Australia, 6009, Australia

  • Local Institution - 0099

    Los Angeles, California, 90033, United States

  • Local Institution - 0100

    Atlanta, Georgia, 30342, United States

  • Local Institution - 0101

    Marietta, Georgia, 30060, United States

  • Local Institution - 0102

    Toulouse, 31059, France

Conditions

Explore the condition pages connected to this study.