Can a vitamin pill reverse hair loss from Weight-Loss drugs?

NCT ID NCT07783113

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
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First seen Aug 24, 2026 · Last updated Aug 28, 2026 · Updated 3 times

Summary

This trial investigates whether a dietary supplement can reduce hair loss in women who experience telogen effluvium—a type of temporary shedding—while taking GLP-1 medications like semaglutide or tirzepatide. Over 120 days, participants will take the supplement daily, and researchers will measure hair growth and density using clinical exams, hair analysis (trichogram), and questionnaires. The study aims to see if the supplement can shift hair follicles back into a growing phase, potentially easing a common side effect of these weight-loss drugs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A dietary supplement containing vitamins, minerals, amino acids, and silicon
What this could lead to
If effective, this supplement could offer a simple, non-prescription way to reduce hair shedding in people taking GLP-1 weight-loss drugs.
What could go wrong
This is a small, open-label study without a placebo group, so results may be biased. The supplement may not significantly improve hair loss, and individual responses can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 60 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female participants aged 20 to 60 years. * Dry, normal, combination, or oily scalp type. * Clinical diagnosis of telogen effluvium associated with the use of GLP-1 receptor agonists (semaglutide or tirzepatide), diagnosed by a dermatologist and confirmed by trichogram analysis. * Hair length of at least 3 cm. * Use of GLP-1 receptor agonists (semaglutide or tirzepatide) for at least 3 months prior to enrollment. * Intact skin in the study area (scalp). * Use of GLP-1 receptor agonists approved by ANVISA and commercially available in Brazil. * Under regular medical supervision during the study period. * Loss of at least 5% of initial body weight prior to enrollment. * Willingness to maintain the same hairstyle, haircut, and hair care habits throughout the study. * Willingness to comply with all study procedures and requirements. * Ability to provide written informed consent. Exclusion Criteria: * Pregnancy, breastfeeding, postpartum period up to 6 months, or intention to become pregnant during the study. * Scalp conditions or skin marks that may interfere with study assessments. * Known allergy or hypersensitivity to any component of the investigational product or similar products. * Active scalp disorders that could interfere with study evaluations, including scarring alopecia, alopecia areata, folliculitis decalvans, psoriasis, moderate-to-severe seborrheic dermatitis, or eczema. * Use of nonsteroidal anti-inflammatory drugs, corticosteroids, antihistamines, photosensitizing agents, or immunosuppressants within 2 weeks before enrollment. * Ongoing radiotherapy or chemotherapy treatment. * Hair chemical procedures within 30 days prior to enrollment. * Recent use or dose adjustment of medications known to induce telogen effluvium. * Use of dietary supplements for hair loss within the previous 3 months. * Use of hair loss treatments or hair cycle modulators (e.g., minoxidil, finasteride, dutasteride, spironolactone) within the previous 3 months. * Hair transplantation within the previous 18 months. * Use of topical dermatological products for therapeutic or specific cosmetic purposes on the study area (scalp), such as hair tonics, topical minoxidil, medicated lotions, or acid-based treatments, within 48 hours prior to study initiation. * Initiation, discontinuation, or modification of hormone therapy within the previous 3 months. * Uncontrolled systemic diseases, including diabetes, lupus, thyroid disorders, anemia, or documented iron deficiency. * Bariatric surgery within the previous 12 months. * Hair loss associated with COVID-19 infection within the previous 6 months. * Hospitalization within the previous 6 months. * Major physical or psychological stressors within the previous 3 months. * Uncontrolled endocrine disorders. * History or evidence of alcohol or substance abuse. * Immunosuppression caused by medications or active diseases. * Excessive sun exposure or artificial tanning within 15 days before the baseline visit. * Participation in another clinical study. * Investigator site staff or family members directly involved in the study. * Any condition that, in the investigator's opinion, may compromise participant safety or study integrity.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

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  2. The official record

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Contacts and locations

Locations

  • Kosmoscience Ciência E Tecnologia Cosmética - Ltda

    São Paulo, São Paulo, 13270-180, Brazil

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