Can a simple genetic test get more people on heart-saving statins?
NCT ID NCT07260552
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether giving patients and their doctors a polygenic risk score — a genetic test that estimates future risk of coronary heart disease — helps more people start taking statins to prevent heart problems. Researchers will enroll 200 adults aged 40-69 without prior heart disease or statin use from rural and urban clinics. Half will get the genetic risk score along with standard risk assessment; the other half will get standard assessment alone. The main goal is to see if the genetic information leads to more statin prescriptions and lower cholesterol.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- polygenic risk score (genetic screening tool)
- What this could lead to
- If successful, this could show that using a genetic risk test in primary care helps more people start preventive medication and lower their heart disease risk.
- What could go wrong
- This is a small, early-stage study focused on feasibility and uptake, not on actual heart attacks or deaths. The genetic test may not change behavior or outcomes in real-world settings.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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