New combo therapy aims to halt spread of nasopharyngeal cancer

NCT ID NCT04944914

First seen May 07, 2026 · Last updated Jun 23, 2026 · Updated 9 times

Summary

This phase 3 trial tests whether adding a precise form of radiation (SBRT) to the immunotherapy drug camrelizumab helps control cancer better than camrelizumab alone in people with nasopharyngeal cancer that has spread to a few spots (oligometastatic). About 188 adults whose primary tumor is under control and who have had at least one round of chemotherapy will be randomly assigned to one of two groups. The main goal is to see how long patients live without their cancer getting worse.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

camrelizumab (an immunotherapy drug) and stereotactic body radiotherapy (SBRT, a precise type of radiation)

What this could lead to

If successful, this could show that adding targeted radiation to immunotherapy helps control cancer spread better than immunotherapy alone, potentially improving how long patients live without their cancer getting worse.

What could go wrong

This is a phase 3 trial, but it is still recruiting and results are not yet known. The combination may cause more side effects than immunotherapy alone, and it is only tested in a specific group of patients with limited metastases.

Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.