New wound dressings aim to heal stubborn diabetic and leg ulcers

NCT ID NCT07701590

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial investigates whether two special wound dressings—one made from donated amniotic membrane and another from a synthetic material—can help heal diabetic foot ulcers and venous leg ulcers that have not responded to standard care. Adults aged 18 and older with these hard-to-heal wounds are eligible. The study compares healing rates at 12 weeks against a matched group of patients who received standard treatment alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a saline-hydrated allogeneic dual-layer amniotic membrane product (Microlyte®) or a synthetic, resorbable polymeric wound matrix
What this could lead to
If successful, these dressings could offer better healing options for people with chronic wounds that are hard to treat.
What could go wrong
This is a mid-stage trial with a moderate number of participants, and results may not apply to all wound types. The synthetic matrix contains silver, which could cause rare allergic reactions.

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Conditions

The condition(s) this trial relates to.

Diabetic Foot Foot Injuries injury ulcer of lower limbs

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hope Vascular and Podiatry

    RECRUITING

    Houston, Texas, 77054, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Indiana University Health Methodist Hospital

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NAR Medical and Research

    RECRUITING

    Miami, Florida, 33135, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • North Park Podiatry

    RECRUITING

    San Diego, California, 92104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Nova Medical Services - Research Division LLC

    RECRUITING

    Miami, Florida, 33176, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Solutions Medical Research

    RECRUITING

    Coral Gables, Florida, 33134, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Louis Foot and Ankle, LLC

    RECRUITING

    St Louis, Missouri, 63128, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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