New study aims to unlock why some kids with Crohn's heal fully and others Don't

NCT ID NCT05781152

First seen Sep 30, 2025 · Last updated May 12, 2026 · Updated 22 times

Summary

This study follows 900 children aged 6-17 newly diagnosed with Crohn's disease to see how well their intestines heal after one year of anti-TNF therapy. Researchers will use blood tests, stool samples, colonoscopy, and special MRI scans to track healing. The goal is to understand why some children respond better than others, so doctors can personalize treatment in the future.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

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Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

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  • Cedars-Sinai

    RECRUITING

    Los Angeles, California, 90048, United States

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  • Children's Hospital Western Ontario

    RECRUITING

    London, Ontario, N6A 5W9, Canada

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  • Children's Hospital of Eastern Ontario

    RECRUITING

    Ottawa, Ontario, K1H 8L1, Canada

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  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19146, United States

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  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

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  • Cohen Children's Medical Center of NY

    RECRUITING

    Lake Success, New York, 11042, United States

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  • Columbia University Medical Center

    RECRUITING

    New York, New York, 10032, United States

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  • Connecticut Children's Medical Center

    RECRUITING

    Hartford, Connecticut, 06106, United States

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  • Emory University

    RECRUITING

    Atlanta, Georgia, 30328, United States

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  • Goryeb Children's Hospital/Morristown Medical Center/Atlantic Children's Health

    RECRUITING

    Morristown, New Jersey, 07960, United States

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  • Levine Children's

    RECRUITING

    Charlotte, North Carolina, 28203, United States

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  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

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  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43205, United States

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  • Phoenix Children's Hospital

    RECRUITING

    Phoenix, Arizona, 85016, United States

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  • Rady Children's Hospital - San Diego and University of California, San Diego

    RECRUITING

    San Diego, California, 92123, United States

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  • Rhode Island Hospital

    RECRUITING

    Providence, Rhode Island, 02903, United States

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  • Riley Hospital for Children at Indiana University Health

    RECRUITING

    Indianapolis, Indiana, 46202, United States

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  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

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  • Stollery Children's Hospital

    RECRUITING

    Edmonton, Alberta, T6G 1C9, Canada

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  • The Johns Hopkins Children's Medical Center

    RECRUITING

    Baltimore, Maryland, 21287, United States

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  • Toronto SickKids Hospital

    RECRUITING

    Toronto, Ontario, M5G1X8, Canada

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  • UCSF Benioff Children's Hospitals

    RECRUITING

    San Francisco, California, 94158, United States

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  • UH/Rainbow Babies and Children's Hospital

    RECRUITING

    Cleveland, Ohio, 44106, United States

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  • UPMC Children's Hospital of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

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  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

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Conditions

Explore the condition pages connected to this study.