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Calcium levels may boost key drug for postpartum bleeding

NCT ID NCT06930391

Recruiting now Knowledge-focused Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This lab study uses uterine tissue from 40 women having planned C-sections to see if calcium levels change how well carbetocin (a drug that helps the uterus contract) works. The goal is to find the best calcium level to improve carbetocin's effect, which could help prevent or treat severe bleeding after childbirth. It's an early, ex-vivo study, so results are not yet ready for patient care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
carbetocin and calcium chloride
What this could lead to
If it works, this could guide doctors on using calcium to make carbetocin more effective for preventing or treating severe bleeding after childbirth.
What could go wrong
This is a very early lab study using tissue samples, not patients. Results may not translate to real-world care, and the sample size is small (40 samples).

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Postpartum Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTPARTUM HEMORRHAGE (PRIMARY)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mount Sinai Hospital

    RECRUITING

    Toronto, Ontario, M5G1X5, Canada

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

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