New hope for young leukemia patients: experimental drug combo under study

NCT ID NCT05581030

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study is testing whether adding a drug called calaspargase pegol to standard chemotherapy (Hyper-CVAD) is safe and tolerable for young adults newly diagnosed with acute lymphoblastic leukemia (ALL). About 7 participants will receive the combination after completing the first part of standard chemo. The main goal is to check safety and see if the drug combo can reduce leukemia cells to very low levels.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

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